5-fluoro-dCTP (sodium)
5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase[1].
Product Specifications
Product Name Alternative
5-Fluoro-2′-deoxycytidine 5′-triphosphate (sodium)
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-fluoro-dctp-sodium.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1C[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O)=O
Molecular Formula
C9H13FN3Na2O13P3
Molecular Weight
529.11
References & Citations
[1]Olszewska A, et al. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg Med Chem. 2015 Nov 1;23 (21) :6885-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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