5-fluoro-dCTP
Product Specifications
UNSPSC Description
5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase[1].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-fluoro-dctp.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1C[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Molecular Weight
485.15
References & Citations
[1]Olszewska A, et al. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg Med Chem. 2015 Nov 1;23(21):6885-90.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155869/5-fluoro-dCTP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155869/
Clinical Information
No Development Reported
CAS Number
79671-09-3
Curated Selection
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