5-fluoro-dCTP

5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase[1].

Product Specifications

CAS Number

[79671-09-3]

Product Name Alternative

5-Fluoro-2′-deoxycytidine 5′-triphosphate

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-fluoro-dctp.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1C[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C9H15FN3O13P3

Molecular Weight

485.15

References & Citations

[1]Olszewska A, et al. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg Med Chem. 2015 Nov 1;23 (21) :6885-90.