HPL-IN-1
HPL-IN-1 (compound 2t) is a reversible inhibitor of pancreatic lipase (PL) (IC50=1.86 μM) for anti-obesity research[1].
Product Specifications
CAS Number
[2387374-26-5]
UNSPSC
12352005
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hpl-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)C3=CC(F)=CC(F)=C3O
Molecular Formula
C19H11Cl2F2NO3
Molecular Weight
410.20
References & Citations
[1]Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413.. .
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155836/hPL-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155836/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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