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H-NTPDase-IN-5

H-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8) .

Product Specifications

CAS Number

2939932-93-9

UNSPSC

12352005

Target

NTPDase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-ntpdase-in-5.html

Solubility

10 mM in DMSO

Smiles

C1(OCC2=CC=CC=C2)=CC=C(C=C1)C3=CSC4=C3N=CN=C4N5CCOCC5

Molecular Formula

C23H21N3O2S

Molecular Weight

403.50

References & Citations

[1]Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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