H-NTPDase-IN-5
H-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8) .
Product Specifications
CAS Number
2939932-93-9
UNSPSC
12352005
Target
NTPDase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-ntpdase-in-5.html
Solubility
10 mM in DMSO
Smiles
C1(OCC2=CC=CC=C2)=CC=C(C=C1)C3=CSC4=C3N=CN=C4N5CCOCC5
Molecular Formula
C23H21N3O2S
Molecular Weight
403.50
References & Citations
[1]Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
