H-NTPDase-IN-3

H-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8) .

Product Specifications

CAS Number

[2939933-10-3]

UNSPSC

12352005

Target

NTPDase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-ntpdase-in-3.html

Solubility

10 mM in DMSO

Smiles

C1(C2=NC=NC3=C2SC=C3C4=CC=CN=C4)=CC=CN=C1

Molecular Formula

C16H10N4S

Molecular Weight

290.34

References & Citations

[1]Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.