TZ4M
TZ4M is a 2,4-thiazolidinedione (TZD) -based anti-ADV agent with neuroprotective effects. TZ4M exhibits AChE inhibition in human plasma. TZ4M improves memory and cognitive impairment in adult rats in a scopolamine -induced Alzheimer-type model[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tz4m.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC(C1=CC=CC=C1)=O)C/2=O)SC2=C\C3=CC=C(OC)C=C3
Molecular Formula
C19H15NO4S
Molecular Weight
353.39
References & Citations
[1]Taheri M, et al. Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats. ACS Chem Neurosci. 2023 Sep 6;14 (17) :3156-3172.. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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