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TZ4M

TZ4M is a 2,4-thiazolidinedione (TZD) -based anti-ADV agent with neuroprotective effects. TZ4M exhibits AChE inhibition in human plasma. TZ4M improves memory and cognitive impairment in adult rats in a scopolamine -induced Alzheimer-type model[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tz4m.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC(C1=CC=CC=C1)=O)C/2=O)SC2=C\C3=CC=C(OC)C=C3

Molecular Formula

C19H15NO4S

Molecular Weight

353.39

References & Citations

[1]Taheri M, et al. Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats. ACS Chem Neurosci. 2023 Sep 6;14 (17) :3156-3172.. .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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