DPP
DPP is a Platinum (IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].
Product Specifications
CAS Number
2668267-47-6
UNSPSC
12352005
Target
Apoptosis; JAK; STAT
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dpp.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(OC)=CC(/C=C/C(C=C2)=CC=C2OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[O-]C(COC(C=C3)=CC=C3/C=C/C4=CC(OC)=CC(OC)=C4)=O)=O)=C1
Molecular Formula
C36H40Cl2N2O10Pt
Molecular Weight
926.70
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Schizosaccharomyces Pombe wis1 Protein (aa 1-605)
SYN1 (Synapsin I, SYN1a, SYN1b, SYNI) (MaxLight 550)
Mouse Monoclonal CD19 Antibody (CVID3/155) [mFluor Violet 500 SE]
Vmn2r84 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
