H-NTPDase-IN-2

H-NTPDase-IN-2 (compound 3l) is a pan-inhibitor of h-NTPDase, with IC50s of 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8), respectively[1].

Product Specifications

CAS Number

[2939933-03-4]

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-ntpdase-in-2.html

Solubility

10 mM in DMSO

Smiles

CN(CC1=CC=CC=C1)C2=C3SC=C(C4=CC=NC=C4)C3=NC=N2

Molecular Formula

C19H16N4S

Molecular Weight

332.42

References & Citations

[1]Zaman G, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165. .