MMAF (sodium) (GMP)
MMAF sodium GMP is a GMP grade MMAF (sodium). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A[1][2][3].
Product Specifications
CAS Number
1799706-65-2
Product Name Alternative
Monomethylauristatin F (sodium) (GMP)
UNSPSC
12352005
Target
ADC Payload; Microtubule/Tubulin
Type
GMP Small Molecules
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmaf-sodium-gmp.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(O[Na])=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
Molecular Formula
C39H64N5NaO8
Molecular Weight
753.94
References & Citations
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Frequently Asked Questions
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