What is the catalog number for MTP?

The catalog number for MTP is HY-155785.

What sizes are available for MTP?

MTP is available in the following size(s): 1 Each.

MTP is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTP?

MTP is manufactured by QuantiMol.

What is the estimated delivery time for MTP?

Estimated delivery time for MTP is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTP?

The safety data sheet for MTP is available here: http://file.medchemexpress.com/batch_PDF/HY-155785/.

MTP

MTP is a PKM2 inhibitor. MTP induces cancer cell apoptosis by modulating caspase-3 activation. MTP induces autophagy and increases ROS generation. MTP also inhibits JAK2 signaling. MTP can be used for research of oral squamous cell carcinoma[1].

Product Specifications

CAS Number

2377372-62-6

UNSPSC

12352005

Target

Apoptosis; Autophagy; JAK; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mtp.html

Solubility

10 mM in DMSO

Smiles

C#CC(NC1=CC=C(C=C1)N2N=C(C=C2C3=CC=C(C=C3)C4=CC=C(C=C4)C(F)(F)F)CCC(NC)=O)=O

Molecular Formula

C29H23F3N4O2

Molecular Weight

516.51

References & Citations

[1]Weng JR, et al. A PKM2 inhibitor induces apoptosis and autophagy through JAK2 in human oral squamous cell carcinoma cells. Chem Biol Interact. 2023 Aug 1;380:110538.