Anti-neuroinflammation agent 1
Anti-neuroinflammation agent 1 is a potent anti-neuroinflammation agent that regulates polarization BV2 microglia cells from M1 phenotype to M2 phenotype[1].
Product Specifications
CAS Number
2968412-77-1
UNSPSC
12352005
Target
Interleukin Related; NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anti-neuroinflammation-agent-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C(OC)=C1)C3=C(CCO2)C(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=C(N)N3.Cl
Molecular Formula
C22H20ClF6N3O3
Molecular Weight
523.86
References & Citations
[1]Yang Yang, et al. Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization. Eur J Med Chem. 2023 Jul 27;259:115688.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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