AChE-IN-37
AChE-IN-37 (compound A2) is anacetylcholinesterase inhibitorswith an IC50 of 0.23 μM. AChE-IN-37 effects ROS levels and gene expression of NRF2[1].
Product Specifications
CAS Number
[2978753-64-7]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-37.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C([N+]([O-])=O)C=C1)(OC2=CC=C3C(/C(OC3=C2)=C/C4=CC=C(Cl)C=C4)=O)=O
Molecular Formula
C21H12ClNO7S
Molecular Weight
457.84
References & Citations
[1]Abdolrahim Pourparizi, et al. Synthesis of aurone sulfonate derivatives: Evaluation of their cholinesterase inhibition, neuroprotective effects, and expression of oxidative stress-related genes. Journal of Molecular Structure.2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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