Antitumor agent-115

Antitumor agent-115 (SS-12) is an effective anti-tumor compound with an IC50 value of 0.34 μM-24.14 μM for cell line 4T1. Antitumor agent-115 can block the cell cycle of mouse breast cancer cell line 4T1, reduce the mitochondrial membrane potential, and induce apoptosis, and the IC50 value is 8-25 μmol/L for cell viability. Antitumor agent-115 can be used for breast cancer research[1].

Product Specifications

CAS Number

[2759277-20-6]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-115.html

Solubility

10 mM in DMSO

Smiles

C[N+]1(C)C(C(OCCCCCCCCCCCC)=O)CCC1.[Cl-]

Molecular Formula

C19H38ClNO2

Molecular Weight

347.96

References & Citations

[1]Zeng H, et al. Synthesis, characterization and anti-breast cancer activities of stachydrine derivatives. Eur J Med Chem. 2023 Jul 26;259:115679.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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