CB2 PET Radioligand 1
CB2 PET Radioligand 1 (compound [18F]9) is a PET Radioligand targeting to hCB2 (Ki=7.7 nM) . CB2 PET Radioligand 1 is prepared with Cu-mediated 18F-fluorination. CB2 PET Radioligand 1 shows high brain uptake in a murine model of neuroinflammation[1].
Product Specifications
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cb2-pet-radioligand-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(NC2=NC=C(C(N3CCC(CC3)(F)F)=O)C4=C2C=CN4C)=CC=C1
Molecular Formula
C20H19F3N4O
Molecular Weight
388.39
References & Citations
[1]Kallinen A, et al. Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands. ACS Chem Neurosci. 2023 Aug 16;14 (16) :2902-2921.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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