PI3K-IN-41
Product Specifications
UNSPSC Description
PI3K-IN-41 (compound 2) is a photocaged compound, as well as a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties. PI3K-IN-41 has potential to be used in precisely controlled cancer therapeutics. PI3K-IN-41 exhibits potent PI3K ihibition upon UV light irradiation, and enhances antitumor effect[1].
Target Antigen
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-in-41.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(COC2=CC3=C(C=C(C(O3)=O)CN(S(C4=C(C=C(C=C4)F)F)(=O)=O)C5=C(N=CC(C6=CC7=C(N=CN=C7C(OC8CCOCC8)=C6)C)=C5)OC)C=C2)=C(C=C1OC)[N+]([O-])=O
Molecular Weight
911.88
References & Citations
[1]Tian H, et al. Discovery of a Novel Photocaged PI3K Inhibitor Capable of Real-Time Reporting of Drug Release. ACS Med Chem Lett. 2023 Jul 24;14(8):1100-1107.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155730/PI3K-IN-41-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155730/
Clinical Information
No Development Reported
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