SDH-IN-6

SDH-IN-6 (compound 6i) is a potent succinate dehydrogenase (SDH) inhibitor. SDH-IN-6 has antifungal activity against Valsa mali with an EC50 value of 1.77 mg/L[1].

Product Specifications

CAS Number

[3010257-33-4]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sdh-in-6.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1)=CC=C1C(C2=NC(C)=C(S2)C)NC(C(C(C(F)F)=N3)=CN3C)=O

Molecular Formula

C18H17ClF2N4OS

Molecular Weight

410.87

References & Citations

[1]Li M, et, al. Design, Synthesis, and Evaluation of Antifungal Bioactivity of Novel Pyrazole Carboxamide Thiazole Derivatives as SDH Inhibitors. J Agric Food Chem. 2023 Aug 2;71 (30) :11365-11372.