HDAC-IN-61
Product Specifications
UNSPSC Description
HDAC-IN-61 (compound 12k) is a potent and orally active HDAC inhibitor. HDAC-IN-61 has anticancer active with an IC50 value of 30 nM for Bel-7402 cell. HDAC-IN-61 can be used in research of cancer[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-61.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N1CCC(C2=CC=C(C=C2O3)OC)=C3C1)CC4=CC=CC=C4)NC5=CC=C(C=C5)C(NO)=O
Molecular Weight
485.53
References & Citations
[1]Lai Z, et, al. Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-c]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma. J Med Chem. 2023 Aug 10;66(15):10791-10807.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155695/HDAC-IN-61-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155695/
Clinical Information
No Development Reported
Curated Selection
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