PDE4-IN-13
PDE4-IN-13 is a PDE4 inhibitor with an IC50 of 1.56 μM. PDE4-IN-13 shows anti-inflammatory and antioxidant properties, and can be used for chronic obstructive pulmonary disease (COPD) research[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde4-in-13.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(O)C(O)=C1)/C=C/C2=CC=C(OC)C(OCC3CC3)=C2
Molecular Formula
C20H20O5
Molecular Weight
340.37
References & Citations
[1]Youzhi Wang, et al. Design and synthesis of a novel class of PDE4 inhibitors with antioxidant properties as bifunctional agents for the potential treatment of COPD. Eur J Med Chem. 2023 Aug 5;256:115374.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155692/PDE4-IN-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155692/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
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