Tubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) is a strong and effective Tubulin inhibitor, with an IC50 value of 0.21 μM. Tubulinpolymer-in-44 induces apoptosis by arresting G2/M phase, which can be used for cancer research.
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-44.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C(OC)=CC(C2=NN3C(SC=C3C4=CC(Cl)=CC(Cl)=C4)=N2)=C1
Molecular Formula
C19H15Cl2N3O3S
Molecular Weight
436.31
References & Citations
[1]Na Li, et al.Discovery of 6-aryl-2- (3,4,5-trimethoxyphenyl) thiazole[3,2-b][1,2,4]
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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