TPPC
TPPC, a porphyrin cholesterol conjugate, can render cancer cells more sensitive to ICIs. TPPC can enhance photodynamic immunotherapy toward lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tppc.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC(O[C@@H]1CC2=CC[C@]([C@@](CC[C@@H]3[C@H](C)CCCC(C)C)([H])[C@]3(C)CC4)([H])[C@@]4([H])[C@@]2(C)CC1)=O)NC5=CC=C(/C6=C(N/7)\C=CC7=C(C8=CC=CC=C8)\C(C=C/9)=NC9=C(C%10=CC=C(/C(C%11=CC=CC=C%11)=C%12N=C6C=C\%12)N%10)\C%13=CC=CC=C%13)C=C5
Molecular Formula
C75H79N5O3
Molecular Weight
1098.46
References & Citations
[1]Zhao M, et al. Porphyrin Cholesterol Conjugates for Enhanced Photodynamic Immunotherapy toward Lung Cancer. ACS Appl Mater Interfaces. 2023 Aug 2;15 (30) :35927-35938.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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