Anti-inflammatory agent 48

Anti-inflammatory agent 48 is an anti-inflammatory agent based on its role in inhibiting the NF-κB signaling pathway and activating HO-1 expression[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-48.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=CC(Cl)=C1NC2=CC=CC=C2CC(OC3=C(OC)C=C(CC=C)C=C3)=O

Molecular Formula

C24H21Cl2NO3

Molecular Weight

442.33

References & Citations

[1]Wei Wang, et al. Diclofenac and eugenol hybrid with enhanced anti-inflammatory activity through activating HO-1 and inhibiting NF-κB pathway in vitro and in vivo. Eur J Med Chem. 2023 Nov 5;259:115669.