VEGFR-2-IN-31
Product Specifications
UNSPSC Description
VEGFR-2-IN-31 (compound 3i) is a potent VEGFR-2 inhibitor (IC50=8.93 nM), and an anti-prostate cancer agent. VEGFR-2-IN-31 arrests cell cycle at the S-phase and induces apoptosis.
Target Antigen
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-31.html
Solubility
10 mM in DMSO
Smiles
O=C1NN=C(C2=CC=CC=C2)/C1=N/NC3=CC=C(C=C3F)F
Molecular Weight
300.26
References & Citations
[1]Soliman DH, et al. Design, synthesis, and docking studies of novel pyrazole-based scaffolds and their evaluation as VEGFR2 inhibitors in the treatment of prostate cancer. RSC Adv. 2023 Jul 10;13(30):20443-20456.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155609/VEGFR-2-IN-31-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155609/
Clinical Information
No Development Reported
Curated Selection
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