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H-NTPDase8-IN-1

H-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM) . h-NTPDases8 is involved in a variety of physiological and pathological functions, such as thrombosis, diabetes, inflammation, and cancer[1].

Product Specifications

UNSPSC

12352005

Target

NTPDase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/h-ntpdase8-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC(S(=O)(NC2CC2)=O)=CC=C1Cl

Molecular Formula

C10H10ClNO4S

Molecular Weight

275.71

References & Citations

[1]Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13 (30) :20909-20915.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-155597/h-NTPDase8-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-155597/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[716358-51-9]

Available Sizes

Curated Selection

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