H-NTPDase8-IN-1
H-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM) . h-NTPDases8 is involved in a variety of physiological and pathological functions, such as thrombosis, diabetes, inflammation, and cancer[1].
Product Specifications
CAS Number
[716358-51-9]
UNSPSC
12352005
Target
NTPDase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/h-ntpdase8-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC(S(=O)(NC2CC2)=O)=CC=C1Cl
Molecular Formula
C10H10ClNO4S
Molecular Weight
275.71
References & Citations
[1]Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13 (30) :20909-20915.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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