SNM1A-IN-1
SNM1A-IN-1 (compound 11a) is an inhibtor of SNM1A (a DNA damage repair enzyme with cytotoxicity) [1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/snm1a-in-1.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](CNC(CCC(O)=O)=O)O[C@H]1N(C(N2)=O)C=C(C)C2=O
Molecular Formula
C14H19N3O8
Molecular Weight
357.32
References & Citations
[1]Arbour CA, et al. Deploying solid-phase synthesis to access thymine-containing nucleoside analogs that inhibit DNA repair nuclease SNM1A. Org Biomol Chem. 2023 Jul 19;21 (28) :5873-5879.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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