MDM2/XIAP-IN-3
Product Specifications
CAS Number
2925583-17-9
UNSPSC Description
MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].
Target Antigen
IAP; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-xiap-in-3.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC2=C(NC(C3=CC=C(C(C(C)C)=O)C=C3)C4C2OCC4)C=C1)(NC5=CC=CC(C(C)=O)=C5)=O
Molecular Weight
518.62
References & Citations
[1]Albadari N, et al. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. Eur J Med Chem. 2023 Jul 5;255:115423.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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