Chitin synthase inhibitor 13
Chitin synthase inhibitor 13 (compound 12g) is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. Chitin synthase inhibitor 13 exhibits a broad-spectrum of antifungal activity[1].
Product Specifications
CAS Number
2925228-79-9
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chitin-synthase-inhibitor-13.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C([N+]([O-])=O)C=C1)/C=C/C(NC2=CC3=C(NC4(CSCC4)NC3=O)C=C2)=O
Molecular Formula
C21H19N5O5S
Molecular Weight
453.47
References & Citations
[1]Du C, et, al. Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2023 Jul 5;255:115388.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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