Anti-inflammatory agent 47

Flo8 is a potent anti-inflammatory and antioxidant compound. Flo8 inhibits the release of intracellular reactive oxygen species (ROS) and nitric oxide (NO) and suppresses neuronal apoptotic by inhibiting inflammatory and apoptotic signaling pathways. Flo8 can be used for Parkinson's Disease (PD) research[1].

Product Specifications

CAS Number

[2925288-12-4]

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-47.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C)=C(C2=CC=CC=C2)OC3=C1C=CC=C3C4=NC(C5=CC=CC(C)=C5)=NO4

Molecular Formula

C25H18N2O3

Molecular Weight

394.42

References & Citations

[1]Shen ZB, et al. Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease. Eur J Med Chem. 2023 Jul 5;255:115417.