GPR119 agonist 2
GPR119 agonist 2 (compound 43) is an orally active GPR119 agonist. GPR119 agonist 2 shows good pharmacokinetic characteristics in rodents and can effectively improve glucose tolerance in mice and rats. GPR119 agonist 2 has the potential to study type 2 diabetes[1].
Product Specifications
CAS Number
[1384951-03-4]
UNSPSC
12352005
Target
GPR119
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gpr119-agonist-2.html
Solubility
10 mM in DMSO
Smiles
CC(C)C1=NOC(N2CCC(CC2)OC3=NC=NC4=C3SC=C4C5=C(C=C(C=C5)S(=O)(C)=O)F)=N1
Molecular Formula
C23H24FN5O4S2
Molecular Weight
517.60
References & Citations
[1]Kim H, et al. Discovery of orally active sulfonylphenyl thieno [3, 2-d] pyrimidine derivatives as GPR119 agonists. Eur J Med Chem. 2023: 115584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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