HBV-IN-34
HBV-IN-34 (compound 17i) is a potent HBsAg production inhibitor. HBV-IN-34 exhibits excellent in vitro anti-HBV potency, with an EC50 of 0.018 μM and 0.044 μM for HBV DNA and HBsAg, respectively[1].
Product Specifications
CAS Number
[2716906-45-3]
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hbv-in-34.html
Solubility
10 mM in DMSO
Smiles
FC1=NC(N2[C@@]3([H])C4=CN=C(C5=NC=CC=N5)N=C4C[C@]2([H])CC3)=CC(N6CC(C6)F)=C1
Molecular Formula
C21H19F2N7
Molecular Weight
407.42
References & Citations
[1]Zhang L, et, al. Discovery, optimization and biological evaluation of novel HBsAg production inhibitors. Eur J Med Chem. 2023 Aug 5;256:115387.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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