Antitumor agent-110
Antitumor agent-110 (compound 13) is an anticancer imidazotetrazine with good permeability properties. Antitumor agent-110 arrests cell cycel at G2/M phase, and induces apoptosis[1]. Antitumor agent-110 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2563879-93-4
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-110.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C=N2)N(N=NC1=C2C3=NC=CS3)CC#C
Molecular Formula
C10H6N6OS
Molecular Weight
258.26
References & Citations
[1]Summers HS, et al. Discovery of new imidazotetrazinones with potential to overcome tumor resistance. Eur J Med Chem. 2023 Sep 5;257:115507.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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