Antimalarial agent 28

Antimalarial agent 28 (Compound 2i) is an antiplasmodial agent. Antimalarial agent 28 inhibits P. berghei, with IC50s of 0.561 μM, 0.14 μM, 4.34 μM for Liver stage, early gametocytes and ring stages of P. falciparum[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimalarial-agent-28.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCCCNC1=CC(OC)=CC2=CC3=CC=C(Cl)C=C3N=C12)/C=C/C4=CC=CC(F)=C4

Molecular Formula

C27H25ClFN3O2

Molecular Weight

477.96

References & Citations

[1]Fonte M, et al. New 4- (N-cinnamoylbutyl) aminoacridines as potential multi-stage antiplasmodial leads. Eur J Med Chem. 2023 Oct 5;258:115575.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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