Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

FY-21

FY-21 is a selective inhibitor of LSD1 (IC50=340 nM), with anti-proliferation and anti-colony formation activities. FY-21 enhances p53 expression, down-regulates HOXA9 and MEIS1 expression. FY-21 also induces leukemia cell differentiation to exhibts antitumor activity[1].

Product Specifications

CAS Number

3049681-20-8

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fy-21.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C=C2C(NCCC2=C1)C3=CC=C(C=C3)[N+]([O-])=O)O.FC(C(O)=O)(F)F

Molecular Formula

C17H15F3N2O6

Molecular Weight

400.31

References & Citations

[1]Yang C, et al. Discovery of new tetrahydroisoquinolines as potent and selective LSD1 inhibitors for the treatment of MLL-rearranged leukemia. Eur J Med Chem. 2023 Sep 5;257:115516.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TTF-1 Antibody / NKX2.1
F40894-0.08ML 0.08 mL

TTF-1 Antibody / NKX2.1

Sign In for Pricing
View Details
Rabbit Polyclonal BAFFR/TNFRSF13C Antibody [Janelia Fluor 549]
NBP1-77234JF549 0.1 mL

Rabbit Polyclonal BAFFR/TNFRSF13C Antibody [Janelia Fluor 549]

Sign In for Pricing
View Details
Gm11938 (NM_001127354) Mouse Tagged ORF Clone
MG213288 10 µg

Gm11938 (NM_001127354) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
Recombinant Burkholderia xenovorans Protein MraZ (mraZ)
MBS1370364-01 0.02 mg (E-Coli)

Recombinant Burkholderia xenovorans Protein MraZ (mraZ)

Sign In for Pricing
View Details
Recombinant Burkholderia xenovorans Protein MraZ (mraZ)
MBS1370364-02 0.1 mg (E-Coli)

Recombinant Burkholderia xenovorans Protein MraZ (mraZ)

Sign In for Pricing
View Details
Recombinant Burkholderia xenovorans Protein MraZ (mraZ)
MBS1370364-03 0.02 mg (Yeast)

Recombinant Burkholderia xenovorans Protein MraZ (mraZ)

Sign In for Pricing
View Details