Anticancer agent 134

Anticancer agent 134 (compound 6a) is a environment-sensitive fluorescent probe and an apoptosis inducer, making a distinction between the tumor and normal tissues. Anticancer agent 134 localizes to the nuclear bodies in tumor slices[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-134.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1)=CC=C1C2=N[C@@H](CC(NCCCNS(C3=C(C=CC=C4N(C)C)C4=CC=C3)(=O)=O)=O)C5=NN=C(C)N5C6=C2C(C)=C(C)S6

Molecular Formula

C34H36ClN7O3S2

Molecular Weight

690.28

References & Citations

[1]Gao Y, et al. Establishment of environment-sensitive probes targeting BRD3/BRD4 for imaging and therapy of tumor. Eur J Med Chem. 2023 Sep 5;257:115478.