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DprE1-IN-7

DprE1-IN-7 (Compound 64) is a DprE1 inhibitor. DprE1-IN-7 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM) . DprE1-IN-7 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-7 has high microsomal stability and medium clearance[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dpre1-in-7.html

Solubility

10 mM in DMSO

Smiles

NC1=NC(N2CCOCC2)=NC3=C1N(CC4=CC=C5C=CC=CC5=C4)C=N3

Molecular Formula

C20H20N6O

Molecular Weight

360.41

References & Citations

[1]Finger V, et al. 2,6-Disubstituted 7- (naphthalen-2-ylmethyl) -7H-purines as a new class of potent antitubercular agents inhibiting DprE1. Eur J Med Chem. 2023 Oct 5;258:115611.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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