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CB2 receptor antagonist 4

CB2 receptor antagonist 4 (compound (R) -1) is a CB2R-selective inverse agonist with a Kd value of 39 nM[1].

Product Specifications

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cb2-receptor-antagonist-4.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC(OC)=C([C@@]2([H])C=C(CN)[C@@H]3C(C)(C)[C@H]2C3)C(OC)=C1)(C)[C@H](CCCCCN=[N+]=[N-])C4=CC=CC=C4

Molecular Formula

C33H46N4O2

Molecular Weight

530.74

References & Citations

[1]Erick Carreira, et al. Flipping the GPCR Switch: Structure–Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists. ChemRxiv. 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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