CB2 receptor antagonist 3
CB2 receptor antagonist 3 (compound (S) -1) is an inverse agonist of the cannabinoid receptor CB2R with Kd=39 nM. CB2 receptor antagonist 3 can be used as a tool to synthesize a variety of CB2R probes[1].
Product Specifications
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cb2-receptor-antagonist-3.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC(OC)=C([C@@]2([H])C=C(CN)[C@@H]3C(C)(C)[C@H]2C3)C(OC)=C1)(C)[C@@H](CCCCCN=[N+]=[N-])C4=CC=CC=C4
Molecular Formula
C33H46N4O2
Molecular Weight
530.74
References & Citations
[1]Carreira E et al. Flipping the GPCR Switch: Structure–Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists[J]. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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