IMP 243
IMP 243 is a symmetric di-HSG (histamine-succinyl-glycine) bivalent hapten containing a Tscg-Cys ligand and two HSG groups. IMP 243 can be radiolabeled with 99mTc-pertechnetate. IMP 243 can be conjugated to other peptides to design bispecific antibodies (bsMAbs) for cancer research[1].
Product Specifications
CAS Number
391267-29-1
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imp-243.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC(NCC(NCCCC[C@@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCNC([C@H](CS)NC(/C=N\NC(N)=S)=O)=O)=O)CCCCNC(CNC(CCC(NCCC1=CNC=N1)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)NC(C)=O)=O)=O)NCCC3=CNC=N3
Molecular Formula
C57H86N20O14S2
Molecular Weight
1339.55
References & Citations
[1]Sharkey RM, et al. A universal pretargeting system for cancer detection and therapy using bispecific antibody. Cancer Res. 2003 Jan 15;63 (2) :354-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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