CYP2A6-IN-1
CD-6 is a flavonoid CYP2A6 inhibitor (IC50: 1.566 μM) . CYP2A6 inhibits the metabolism of nicotine to cotinine, resulting in an increase in the amount of nicotine available in the blood, leading to increased smoking behavior. CD-6 mediates CYP2A6 inhibition and can be used in research on smoking cessation or smoking-related diseases[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyp2a6-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2OCC(O)=O)OC3=CC=CC=C31
Molecular Formula
C17H12O5
Molecular Weight
296.27
References & Citations
[1]Goyal N et al. Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors. Chem Res Toxicol. 2023 Nov 14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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