CDK2-IN-20
Product Specifications
UNSPSC Description
CDK2-IN-20 (compound 3b) is an inhibitor of CDK2. CDK2-IN-20 has cytotoxicity on tumor cells presenting an IC50 range of 5.52-17.09 µM. CDK2-IN-20 arrests the MCF-7 cell cycle at the S phase and induces apoptosis[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-20.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC=C1C(S2)C(C#N)=C(N)N3C=NC4=C3C2=NC=N4
Molecular Weight
340.79
References & Citations
[1]Ebtehal M Husseiny, et al. Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigations. Bioorg Chem. 2023
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155441/CDK2-IN-20-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155441/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Ribonuclease Inhibitor Antibody (1H23) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/genprice2.png)
NBP1-30167JF549 0.1 mL
Mouse Monoclonal Ribonuclease Inhibitor Antibody (1H23) [Janelia Fluor 549]
Ask
View Details 