ICMT-IN-27
Product Specifications
UNSPSC Description
ICMT-IN-27 (compound 64) is an inhibitor of ICMT (IC50=0.1 μM)[1].
Target Antigen
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-27.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(NCCC2(C3=CC=C(F)C=C3)CCOC(C)(C)C2)=C1
Molecular Weight
357.46
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155430/ICMT-IN-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155430/
Clinical Information
No Development Reported
CAS Number
1313603-11-0
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