ICMT-IN-27
ICMT-IN-27 (compound 64) is an inhibitor of ICMT (IC50=0.1 μM) [1].
Product Specifications
CAS Number
[1313603-11-0]
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-27.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(NCCC2(C3=CC=C(F)C=C3)CCOC(C)(C)C2)=C1
Molecular Formula
C22H28FNO2
Molecular Weight
357.46
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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