ICMT-IN-14
ICMT-IN-14 (compound 50) is an inhibitor of ICMT (IC50=0.025 μM) [1].
Product Specifications
CAS Number
1313602-97-9
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-14.html
Solubility
10 mM in DMSO
Smiles
CC(OCC1)(C)CC1(CCNC2=CC(Cl)=C(F)C=C2)C3=CC=CC=C3
Molecular Formula
C21H25ClFNO
Molecular Weight
361.88
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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