ICMT-IN-2
ICMT-IN-2 (compound 45) is an inhibitor of ICMT (IC50=0.168 μM) [1].
Product Specifications
CAS Number
[1313602-91-3]
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-2.html
Solubility
10 mM in DMSO
Smiles
FC(C=C1)=CC=C1NCCC2(CC(C)(C)OCC2)C3=CC=CC=C3
Molecular Formula
C21H26FNO
Molecular Weight
327.44
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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