Antiproliferative agent-43
Antiproliferative agent-43 (Compound e4) has notable cytotoxic effects against cancer cell lines and causes apoptosis by stopping the cell cycle at G1 phase[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-43.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C[C@H](N(CC2)C)[C@](C=C3OC)([H])[C@@]42CC3=O)C4=C1OCCCCOC(CCCCC(SCC5=CC=CC=C5)CCSCC6=CC=CC=C6)=O
Molecular Formula
C45H57NO6S2
Molecular Weight
772.07
References & Citations
[1]Gao X, et al. Discovery of sinomenine/8-Bis (benzylthio) octanoic acid hybrids as potential anti-leukemia drug candidate via mitochondrial pathway. Bioorg Med Chem Lett. 2023 Nov 7;97:129545.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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