Antiproliferative agent-43

Antiproliferative agent-43 (Compound e4) has notable cytotoxic effects against cancer cell lines and causes apoptosis by stopping the cell cycle at G1 phase[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-43.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C[C@H](N(CC2)C)[C@](C=C3OC)([H])[C@@]42CC3=O)C4=C1OCCCCOC(CCCCC(SCC5=CC=CC=C5)CCSCC6=CC=CC=C6)=O

Molecular Formula

C45H57NO6S2

Molecular Weight

772.07

References & Citations

[1]Gao X, et al. Discovery of sinomenine/8-Bis (benzylthio) octanoic acid hybrids as potential anti-leukemia drug candidate via mitochondrial pathway. Bioorg Med Chem Lett. 2023 Nov 7;97:129545.