PFI-6
PFI-6 is a non-cytotoxic and selective MLLT1/3 probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) . PFI-6 shows IC50 values of 140 nM and 160 nM for MLLT1 and MLLT3, respectively. PFI-6 can serve as a molecular tool to explore the role of MLLT1/3 in various diseases and related genome validation studies[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pfi-6.html
Purity
99.91
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N(C)C)C1=CC=C(C2=CC(C(N[C@H]3C(C=CC=C4)=C4CC3)=O)=NO2)C=C1O
Molecular Formula
C22H21N3O4
Molecular Weight
391.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155412/PFI-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155412/PFI-6-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2675452-91-0]
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