HPSE1-IN-2
HPSE1-IN-2 (compound 2) is a Heparanase-1 (HPSE1) inhibitor that also inhibits exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) activity[1].
Product Specifications
CAS Number
2876926-27-9
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hpse1-in-2.html
Solubility
10 mM in DMSO
Smiles
CO[C@H]1[C@@H]([C@H](C2=NC(CCC3=CC(OC4=CC=CC=C4)=CC=C3)=CN2[C@@H]1C(O)=O)O)O
Molecular Formula
C23H24N2O6
Molecular Weight
424.45
References & Citations
[1]Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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