ALR-38
ALR-38 is a 5-lipoxygenase (5-LOX) inhibitor (IC50: 1.1 μM) with anti-inflammatory activity. ALR-38 effectively reduces ROS levels in neutrophils[1].
Product Specifications
CAS Number
241127-61-7
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alr-38.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(NCC2=C(O)C3=C(C=CC=C3)C(O)=C2)C=C1)OC
Molecular Formula
C19H17NO4
Molecular Weight
323.34
References & Citations
[1]Cerchia C et al. Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening. Eur J Med Chem. 2023 Nov 8;263:115932.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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